Natural Preservative and Pesticide Potantial of White Cheese Isolated Lactic Acid Bacteria: Quorum Quenching, Antibacterial and Antitumor

Abstract

The study aimed to determine the quorum quenching (QQ) and antitumor activity on short-chain AHLs from Quorum Sensing (QS) signals, which is the bacterial communication system, of metabolites obtained by using Lactic acid Bacteria (LAB) in the microbiota of white cheese, a fermented product. While Chromabacterium violaceum CV026 biosensor culture was used to determine the QQ effect on short-chain AHL QS signals; Agrobacterium tumefaciens A136 was used in potato disc studies used to determine its usability as a pesticide. While it was determined that the metabolites produced by all (21) isolates obtained and identified as lactic acid bacteria had a QQ effect on short-chain AHLs, the metabolites of 38.09% (8/21) of the same isolates were found to have antitumor properties. All metabolites were also found to have antibacterial properties against the bacteria Esherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 6538 P, Micrococcus luteus ATCC 4698 and Listeria monocytogenes ATCC 7644. While it was determined that the metabolites produced by lactic acid bacteria have the potential to be used as a preservative and/or surface disinfectant in the food industry with their QQ and antibacterial effects; It has been determined that only 8 of the metabolites have antitumor properties and have the potential to be used as natural pesticides during agricultural practices.